Inside the Mind: Huberman, Sherzai, Dayspring & More on Building a Smarter, Healthier Brain | Masterclass

How can we protect our brain as we age and what can we do today to boost memory, focus, and resilience? In this episode of The Proof, I’ve compiled some of the most impactful conversations I’ve had with leading neuroscientists, neurologists, and brain health researchers to explore exactly that. From building better habits to slowing age-related decline, this masterclass brings you practical, science-backed strategies for optimising brain function, now and in the future. Whether your goal is sharper mental clarity, prevention of neurodegenerative disease, or simply staying sharp for the long haul, this episode is packed with insights you can use right away. You’ll learn: • How neuroplasticity allows your brain to adapt and change at any age • The role of movement and VO₂ max in protecting cognitive performance • How omega-3s and dietary fats impact brain structure and function • What APOE4 means for your risk of Alzheimer’s and why genetics aren’t destiny • The link between cardiovascular health, lipoproteins, and dementia • How the microbiome and inflammation influence brain aging • The surprising ways exercise improves brain volume and connectivity • Why creatine isn’t just for muscles and how it may enhance mental energy and mood • Actionable daily habits to reduce your risk of cognitive decline • The truth about lifestyle vs genetics when it comes to Alzheimer’s disease Featuring insights from Dr Andrew Huberman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Thomas Dayspring, and Dr Kellyann Niotis, this episode distills cutting-edge neuroscience into clear, practical guidance for long-term cognitive health. Thank you for tuning in to today’s episode, and special thanks to the experts featured for their invaluable insights. If you found this episode helpful, please share it with someone who you think might benefit from it. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.